40 Funny Midwest Memes For Anyone Who’s Ever Said “Ope” Without Thinking (April 25, 2025)

The Midwest has a vibe. It’s polite small talk, casseroles at every gathering, and a deep emotional connection to garage refrigerators. It’s saying “ope” instead of “excuse me” and refusing to take the last slice because “someone else might want it.”

These funny memes perfectly capture the weird, lovable spirit of Midwestern life. The weather is unpredictable, the portion sizes are massive, and the passive-aggressiveness is unmatched.

Here are some funny Midwest memes for anyone who’s ever worn shorts in the snow, waved at strangers on the road, or had strong opinions about gas station snacks.


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Nate

Nate Armbruster

When he's not doomscrolling Twitter or writing for Pleated-Jeans, Nate Armbruster writes jokes—and then tells them on stage as a stand-up comedian, where he can watch audiences (hopefully) laugh in real-time.